BTB/POZ domain-containing protein KCTD12 (Q96CX2)

Uniprot ID	Q96CX2
Protein Name	BTB/POZ domain-containing protein KCTD12
Gene Name	KCTD12
Species	Homo sapiens (Human)

Signal peptide^(a)	N	Secretome P^(b)	0.868
Function	Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity). .
GO - Molecular function	identical protein binding : IPI:IntAct RNA binding : HDA:UniProtKB
GO - Biological process	protein homooligomerization : IEA:InterPro

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^{(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.}
^{(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.}