Home Proteins Experiments Diseases Interactions Tutorial
Home
/
Proteins
/
Q92747

Actin-related protein 2/3 complex subunit 1A (Q92747)

Uniprot ID Q92747
Protein Name Actin-related protein 2/3 complex subunit 1A
Gene Name ARPC1A
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.492
Function Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
GO - Molecular function
  • actin binding : TAS:ProtInc
  • actin filament binding : IBA:GO_Central
GO - Biological process
  • actin cytoskeleton organization : TAS:ProtInc
  • Arp2/3 complex-mediated actin nucleation : IBA:GO_Central
  • ephrin receptor signaling pathway : TAS:Reactome
  • Fc-gamma receptor signaling pathway involved in phagocytosis : TAS:Reactome
  • membrane organization : TAS:Reactome
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.