Peroxidasin homolog (Q92626)

Uniprot ID Q92626
Protein Name Peroxidasin homolog
Gene Name PXDN
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b) 0.413
Function Displays low peroxidase activity and is likely to participate in H(2)O(2) metabolism and peroxidative reactions in the cardiovascular system. Plays a role in extracellular matrix formation. .
GO - Molecular function
  • bromide peroxidase activity : IDA:FlyBase
  • extracellular matrix structural constituent : IDA:UniProtKB
  • heme binding : IDA:UniProtKB
  • interleukin-1 receptor antagonist activity : NAS:UniProtKB
  • metal ion binding : IEA:UniProtKB-KW
  • peroxidase activity : IDA:UniProtKB
GO - Biological process
  • basement membrane assembly : ISS:FlyBase
  • collagen fibril organization : IMP:FlyBase
  • extracellular matrix organization : IDA:UniProtKB
  • hydrogen peroxide catabolic process : IDA:UniProtKB
  • immune response : NAS:UniProtKB
  • oxidation-reduction process : IDA:UniProtKB
  • response to oxidative stress : IEA:InterPro
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.