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Q8WX77

Insulin-like growth factor-binding protein-like 1 (Q8WX77)

Uniprot ID Q8WX77
Protein Name Insulin-like growth factor-binding protein-like 1
Gene Name IGFBPL1
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.869
Function IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs in cell culture. They alter the interaction of IGFs with their cell surface receptors (By similarity). May be a putative tumor suppressor protein. .
GO - Molecular function
  • insulin-like growth factor binding : IEA:InterPro
GO - Biological process
  • cellular response to tumor cell : IEP:UniProtKB
  • regulation of cell growth : IEA:InterPro
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.