| Signal peptide(a) |
N |
Secretome P(b) |
0.171 |
| Function |
During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10 (By similarity). Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. . |
| GO - Molecular function |
- actin binding : ISO:MGI
- actin filament binding : ISS:UniProtKB
- actin-dependent ATPase activity : ISO:MGI
- ADP binding : ISO:MGI
- ATP binding : ISO:MGI
- ATPase activity : ISS:UniProtKB
- cadherin binding : ISO:MGI
- calmodulin binding : IEA:UniProtKB-KW
- microfilament motor activity : ISS:UniProtKB
- microtubule binding : IEA:InterPro
- microtubule motor activity : IEA:InterPro
- protein domain specific binding : IPI:UniProtKB
- protein homodimerization activity : ISS:UniProtKB
- protein membrane anchor : ISS:UniProtKB
|
| GO - Biological process |
- actin cytoskeleton reorganization : ISS:UniProtKB
- actin filament-based movement : ISS:UniProtKB
- actomyosin structure organization : ISO:MGI
- angiogenesis : ISS:UniProtKB
- blood vessel endothelial cell migration : ISS:UniProtKB
- cell adhesion : IMP:MGI
- cell morphogenesis involved in differentiation : IMP:MGI
- cell-cell adhesion : IMP:MGI
- cytokinetic process : ISS:UniProtKB
- establishment of meiotic spindle localization : IDA:MGI
- establishment of T cell polarity : IMP:MGI
- in utero embryonic development : IMP:MGI
- meiotic spindle organization : IDA:MGI
- membrane protein ectodomain proteolysis : ISS:UniProtKB
- microtubule-based movement : IEA:InterPro
- monocyte differentiation : ISS:UniProtKB
- myoblast fusion : IMP:MGI
- negative regulation of actin filament severing : IMP:UniProtKB
- phagocytosis, engulfment : IMP:UniProtKB
- platelet formation : ISS:UniProtKB
- positive regulation of protein processing in phagocytic vesicle : IMP:UniProtKB
- protein transport : ISS:UniProtKB
- regulation of cell shape : IMP:MGI
- uropod organization : IMP:MGI
|