Home Proteins Experiments Diseases Interactions Tutorial
Home
/
Proteins
/
Q8R524

Kinesin-like protein KIF1B (Q8R524)

Uniprot ID Q8R524
Protein Name Kinesin-like protein KIF1B
Gene Name Kif1b
Species Rattus norvegicus (Rat)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function Motor for anterograde transport of mitochondria. Has a microtubule plus end-directed motility (By similarity). .Isoform 1 mediates the transport of synaptic vesicles in neuronal cells. {ECO:0000269|PubMed:12204119}.
GO - Molecular function
  • ATP binding : IEA:UniProtKB-KW
  • ATP-dependent microtubule motor activity : IDA:RGD
  • ATP-dependent microtubule motor activity, plus-end-directed : IBA:GO_Central
  • ATPase activity : IDA:RGD
  • kinase binding : IPI:RGD
  • microtubule binding : IBA:GO_Central
  • microtubule motor activity : ISS:UniProtKB
  • scaffold protein binding : IPI:RGD
GO - Biological process
  • anterograde axonal transport : ISS:UniProtKB
  • anterograde neuronal dense core vesicle transport : IGI:ARUK-UCL
  • cellular response to nerve growth factor stimulus : IEP:RGD
  • cytoskeleton-dependent intracellular transport : ISS:UniProtKB
  • lysosome localization : IMP:RGD
  • microtubule-based movement : ISS:UniProtKB
  • mitochondrion transport along microtubule : ISO:RGD
  • neuromuscular synaptic transmission : ISS:UniProtKB
  • neuron-neuron synaptic transmission : ISS:UniProtKB
  • positive regulation of gene expression : IMP:RGD
  • protein localization to cell periphery : IMP:RGD
  • response to rotenone : IEP:RGD
  • retrograde neuronal dense core vesicle transport : IGI:ARUK-UCL
  • transport along microtubule : IDA:RGD
  • vesicle-mediated transport : IBA:GO_Central
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.