Cell adhesion molecule 4 (Q8NFZ8)

Uniprot ID Q8NFZ8
Protein Name Cell adhesion molecule 4
Gene Name CADM4
Species Homo sapiens (Human)
Signal peptide(a) Y Secretome P(b) 0.445
Function Involved in the cell-cell adhesion. Has calcium-and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity. .
GO - Molecular function
  • protein phosphatase binding : IEA:Ensembl
  • receptor tyrosine kinase binding : IEA:Ensembl
  • vascular endothelial growth factor receptor 1 binding : IEA:Ensembl
  • vascular endothelial growth factor receptor 2 binding : IPI:UniProtKB
GO - Biological process
  • cell adhesion : IEA:UniProtKB-KW
  • negative regulation of peptidyl-threonine phosphorylation : IMP:UniProtKB
  • negative regulation of peptidyl-tyrosine phosphorylation : IMP:UniProtKB
  • negative regulation of protein phosphorylation : IMP:UniProtKB
  • negative regulation of vascular endothelial growth factor receptor signaling pathway : ISS:UniProtKB
  • negative regulation of vascular endothelial growth factor signaling pathway : ISS:UniProtKB
  • regulation of cell motility : IMP:UniProtKB
  • regulation of cell population proliferation : IMP:UniProtKB
  • regulation of protein phosphorylation : IMP:UniProtKB
  • regulation of Rac protein signal transduction : IMP:UniProtKB
  • regulation of wound healing : IMP:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.