ELMO domain-containing protein 2 (Q8IZ81)

Uniprot ID	Q8IZ81
Protein Name	ELMO domain-containing protein 2
Gene Name	ELMOD2
Species	Homo sapiens (Human)

Signal peptide^(a)	N	Secretome P^(b)	0.564
Function	Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses. .
GO - Molecular function	GTPase activator activity : IDA:UniProtKB
GO - Biological process	defense response to virus : IEA:UniProtKB-KW regulation of defense response to virus : IDA:UniProtKB

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^{(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.}
^{(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.}