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Q8IYI6

Exocyst complex component 8 (Q8IYI6)

Uniprot ID Q8IYI6
Protein Name Exocyst complex component 8
Gene Name EXOC8
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.403
Function Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
GO - Molecular function
  • phosphatidylinositol binding : IDA:MGI
  • Ral GTPase binding : IDA:MGI
GO - Biological process
  • cellular protein localization : IEA:Ensembl
  • endosome organization : IMP:UniProtKB
  • exocytosis : IDA:MGI
  • extracellular matrix disassembly : IMP:UniProtKB
  • Golgi to plasma membrane transport : IBA:GO_Central
  • protein localization : IBA:GO_Central
  • protein transport : IEA:UniProtKB-KW
  • regulation of macroautophagy : TAS:ParkinsonsUK-UCL
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.