Complement C1r-A subcomponent (Q8CG16)

Uniprot ID	Q8CG16
Protein Name	Complement C1r-A subcomponent
Gene Name	C1ra
Species	Mus musculus (Mouse)

Signal peptide^(a)	Y	Secretome P^(b)	0.738
Function	C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
GO - Molecular function	calcium ion binding : ISO:MGI serine-type endopeptidase activity : ISO:MGI
GO - Biological process	complement activation, classical pathway : IEA:UniProtKB-KW innate immune response : IEA:UniProtKB-KW

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^{(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.}
^{(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.}