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Q8BVI4

Dihydropteridine reductase (Q8BVI4)

Uniprot ID Q8BVI4
Protein Name Dihydropteridine reductase
Gene Name Qdpr
Species Mus musculus (Mouse)
Basic Information Experiments (3) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.735
Function The product of this enzyme, tetrahydrobiopterin (BH-4), is an essential cofactor for phenylalanine, tyrosine, and tryptophan hydroxylases. .
GO - Molecular function
  • 6,7-dihydropteridine reductase activity : ISS:UniProtKB
  • NADH binding : ISO:MGI
  • NADPH binding : ISO:MGI
  • protein homodimerization activity : ISO:MGI
GO - Biological process
  • cellular response to drug : IEA:Ensembl
  • L-phenylalanine catabolic process : IEA:Ensembl
  • liver development : IEA:Ensembl
  • response to aluminum ion : IEA:Ensembl
  • response to glucagon : IEA:Ensembl
  • response to lead ion : IEA:Ensembl
  • tetrahydrobiopterin biosynthetic process : ISS:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.