Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 (Q80XU3)

Uniprot ID	Q80XU3
Protein Name	Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1
Gene Name	Nucks1
Species	Mus musculus (Mouse)

Signal peptide^(a)	N	Secretome P^(b)	0.325
Function
GO - Molecular function	chromatin binding : ISO:MGI double-stranded DNA binding : ISO:MGI single-stranded DNA binding : ISO:MGI transcription factor binding : ISO:MGI transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding : IDA:MGI
GO - Biological process	cellular glucose homeostasis : IMP:ParkinsonsUK-UCL cellular response to X-ray : ISO:MGI chromatin organization : IMP:ParkinsonsUK-UCL double-strand break repair via homologous recombination : ISO:MGI glucose homeostasis : IMP:MGI interstrand cross-link repair : ISO:MGI modulation by host of RNA binding by virus : ISO:MGI modulation by host of viral RNA-binding transcription factor activity : ISO:MGI positive regulation by host of viral genome replication : ISO:MGI positive regulation by host of viral transcription : ISO:MGI positive regulation of insulin receptor signaling pathway : IMP:MGI positive regulation of transcription by RNA polymerase II : IDA:ParkinsonsUK-UCL regulation of DNA replication : ISO:MGI regulation of DNA strand elongation : ISO:MGI regulation of insulin receptor signaling pathway : IMP:ParkinsonsUK-UCL regulation of transcription by RNA polymerase II : IC:ParkinsonsUK-UCL release from viral latency : ISO:MGI replication fork processing : ISO:MGI

^{(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.}
^{(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.}

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