Uniprot ID | Q78ZC9 | ||
Protein Name | Astrocytic phosphoprotein PEA-15 | ||
Gene Name | Pea15 | ||
Species | Rattus norvegicus (Rat) |
Signal peptide(a) | N | Secretome P(b) | |
Function | Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6-and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface (By similarity). . | ||
GO - Molecular function |
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GO - Biological process |
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