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Q6P7A9

Lysosomal alpha-glucosidase (Q6P7A9)

Uniprot ID Q6P7A9
Protein Name Lysosomal alpha-glucosidase
Gene Name Gaa
Species Rattus norvegicus (Rat)
Basic Information Experiments (1) Disease (3) Interactions
Signal peptide(a) Y Secretome P(b)
Function Essential for the degradation of glycogen in lysosomes. Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans. .
GO - Molecular function
  • alpha-1,4-glucosidase activity : IDA:RGD
  • carbohydrate binding : IDA:RGD
  • maltose alpha-glucosidase activity : IEA:UniProtKB-EC
GO - Biological process
  • cardiac muscle contraction : ISO:RGD
  • diaphragm contraction : ISO:RGD
  • glycogen catabolic process : IDA:RGD
  • glycogen metabolic process : ISO:RGD
  • heart morphogenesis : ISO:RGD
  • locomotory behavior : ISO:RGD
  • lysosome organization : ISO:RGD
  • muscle cell cellular homeostasis : ISO:RGD
  • neuromuscular process controlling balance : ISO:RGD
  • neuromuscular process controlling posture : ISO:RGD
  • regulation of the force of heart contraction : ISO:RGD
  • striated muscle contraction : ISO:RGD
  • tissue development : ISO:RGD
  • vacuolar sequestering : ISO:RGD
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.