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Q6LDK0

Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (Q6LDK0)

Uniprot ID Q6LDK0
Protein Name Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
Gene Name Ppp2cb
Species Rattus norvegicus (Rat)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
GO - Molecular function
  • metal ion binding : IEA:UniProtKB-KW
  • phosphoprotein phosphatase activity : IDA:UniProtKB
  • protein C-terminus binding : IPI:RGD
  • protein heterodimerization activity : ISS:UniProtKB
  • protein serine/threonine phosphatase activity : IDA:RGD
GO - Biological process
  • apoptotic mitochondrial changes : ISO:RGD
  • negative regulation of Ras protein signal transduction : IDA:RGD
  • positive regulation of microtubule binding : IMP:ARUK-UCL
  • proteasome-mediated ubiquitin-dependent protein catabolic process : ISO:RGD
  • protein dephosphorylation : IDA:RGD
  • regulation of gene expression : ISO:RGD
  • response to antibiotic : ISO:RGD
  • response to endoplasmic reticulum stress : ISO:RGD
  • response to hydrogen peroxide : ISO:RGD
  • response to lead ion : IDA:ARUK-UCL
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.