Keratin, type I cytoskeletal 10 (Q6IFW6)

Uniprot ID Q6IFW6
Protein Name Keratin, type I cytoskeletal 10
Gene Name Krt10
Species Rattus norvegicus (Rat)
Signal peptide(a) N Secretome P(b)
Function Plays a role in the establishment of the epidermal barrier on plantar skin. .
GO - Molecular function
  • cytoskeletal protein binding : ISO:RGD
  • protein heterodimerization activity : ISS:UniProtKB
  • structural constituent of skin epidermis : ISO:RGD
GO - Biological process
  • cellular response to calcium ion : ISO:RGD
  • epidermis development : ISO:RGD
  • epithelial cell differentiation : ISO:RGD
  • intermediate filament organization : ISO:RGD
  • keratinocyte development : ISO:RGD
  • keratinocyte differentiation : ISO:RGD
  • peptide cross-linking : ISO:RGD
  • positive regulation of epidermis development : ISS:UniProtKB
  • protein heterotetramerization : ISS:UniProtKB
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.