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Q641X3

Beta-hexosaminidase subunit alpha (Q641X3)

Uniprot ID Q641X3
Protein Name Beta-hexosaminidase subunit alpha
Gene Name Hexa
Species Rattus norvegicus (Rat)
Basic Information Experiments (1) Disease (5) Interactions
Signal peptide(a) Y Secretome P(b)
Function Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. .
GO - Molecular function
  • acetylglucosaminyltransferase activity : ISO:RGD
  • beta-N-acetylhexosaminidase activity : ISO:RGD
  • N-acetyl-beta-D-galactosaminidase activity : IEA:UniProtKB-EC
  • protein heterodimerization activity : ISO:RGD
GO - Biological process
  • adult walking behavior : ISO:RGD
  • carbohydrate metabolic process : IEA:InterPro
  • cell morphogenesis involved in neuron differentiation : ISO:RGD
  • ganglioside catabolic process : ISO:RGD
  • glycosaminoglycan biosynthetic process : ISO:RGD
  • glycosaminoglycan metabolic process : ISO:RGD
  • lipid storage : ISO:RGD
  • locomotory behavior : ISO:RGD
  • lysosome organization : ISO:RGD
  • myelination : ISO:RGD
  • neuromuscular process controlling balance : ISO:RGD
  • neuromuscular process controlling posture : ISO:RGD
  • sensory perception of sound : ISO:RGD
  • sexual reproduction : ISO:RGD
  • skeletal system development : ISO:RGD
  • SMAD protein signal transduction : ISO:RGD
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.