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Q62465

Synaptic vesicle membrane protein VAT-1 homolog (Q62465)

Uniprot ID Q62465
Protein Name Synaptic vesicle membrane protein VAT-1 homolog
Gene Name Vat1
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.783
Function Plays a part in calcium-regulated keratinocyte activation in epidermal repair mechanisms. Has no effect on cell proliferation (By similarity). Possesses ATPase activity. Negatively regulates mitochondrial fusion in cooperation with mitofusin proteins (MFN1-2) (By similarity). .
GO - Molecular function
  • oxidoreductase activity : IEA:UniProtKB-KW
  • zinc ion binding : IEA:InterPro
GO - Biological process
  • negative regulation of mitochondrial fusion : ISS:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.