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Q62261

Spectrin beta chain, non-erythrocytic 1 (Q62261)

Uniprot ID Q62261
Protein Name Spectrin beta chain, non-erythrocytic 1
Gene Name Sptbn1
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.247
Function Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
GO - Molecular function
  • actin binding : IEA:UniProtKB-KW
  • ankyrin binding : ISO:MGI
  • cadherin binding : ISO:MGI
  • calmodulin binding : IEA:UniProtKB-KW
  • GTPase binding : ISO:MGI
  • phospholipid binding : IEA:InterPro
  • protein-containing complex binding : ISO:MGI
  • structural constituent of cytoskeleton : ISO:MGI
GO - Biological process
  • actin filament capping : IEA:UniProtKB-KW
  • common-partner SMAD protein phosphorylation : IDA:MGI
  • Golgi to plasma membrane protein transport : ISO:MGI
  • membrane assembly : ISO:MGI
  • mitotic cytokinesis : ISO:MGI
  • plasma membrane organization : ISO:MGI
  • positive regulation of interleukin-2 secretion : ISO:MGI
  • positive regulation of protein localization to plasma membrane : ISO:MGI
  • protein localization to plasma membrane : IMP:BHF-UCL
  • regulation of protein localization to plasma membrane : ISO:MGI
  • regulation of SMAD protein signal transduction : IDA:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.