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Q61792

LIM and SH3 domain protein 1 (Q61792)

Uniprot ID Q61792
Protein Name LIM and SH3 domain protein 1
Gene Name Lasp1
Species Mus musculus (Mouse)
Basic Information Experiments (4) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.746
Function Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity). .
GO - Molecular function
  • actin filament binding : IDA:MGI
  • cadherin binding : ISO:MGI
  • ion transmembrane transporter activity : ISS:UniProtKB
  • metal ion binding : IEA:UniProtKB-KW
GO - Biological process
  • ion transport : ISS:UniProtKB
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.