Follistatin-related protein 1 (Q12841)

Uniprot ID Q12841
Protein Name Follistatin-related protein 1
Gene Name FSTL1
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b) 0.556
Function May modulate the action of some growth factors on cell proliferation and differentiation. Binds heparin (By similarity). .
GO - Molecular function
  • calcium ion binding : IEA:InterPro
  • heparin binding : TAS:ProtInc
GO - Biological process
  • BMP signaling pathway : TAS:Reactome
  • cell differentiation : IBA:GO_Central
  • cellular protein metabolic process : TAS:Reactome
  • multicellular organism development : IBA:GO_Central
  • post-translational protein modification : TAS:Reactome
  • regulation of BMP signaling pathway : IBA:GO_Central
  • response to starvation : IEA:Ensembl
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.