Thrombospondin-2 (Q03350)

Uniprot ID Q03350
Protein Name Thrombospondin-2
Gene Name Thbs2
Species Mus musculus (Mouse)
Signal peptide(a) Y Secretome P(b) 0.54
Function Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties. .
GO - Molecular function
  • calcium ion binding : IEA:InterPro
  • heparin binding : IEA:UniProtKB-KW
GO - Biological process
  • cell adhesion : IEA:UniProtKB-KW
  • extracellular matrix organization : IEA:InterPro
  • negative regulation of angiogenesis : IMP:UniProtKB
  • positive regulation of synapse assembly : ISO:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.