Fibulin-2 (P98095)

Uniprot ID P98095
Protein Name Fibulin-2
Gene Name FBLN2
Species Homo sapiens (Human)
Signal peptide(a) Y Secretome P(b) 0.613
Function Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108). .
GO - Molecular function
  • calcium ion binding : TAS:ProtInc
  • extracellular matrix binding : IEA:Ensembl
  • extracellular matrix structural constituent : TAS:ProtInc
GO - Biological process
  • extracellular matrix organization : IEA:InterPro
  • positive regulation of cell-substrate adhesion : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.