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P97821

Dipeptidyl peptidase 1 (P97821)

Uniprot ID P97821
Protein Name Dipeptidyl peptidase 1
Gene Name Ctsc
Species Mus musculus (Mouse)
Basic Information Experiments (3) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.712
Function Thiol protease. Has dipeptidylpeptidase activity. Can act as both an exopeptidase and endopeptidase. Can degrade glucagon. Plays a role in the generation of cytotoxic lymphocyte effector function.
GO - Molecular function
  • chaperone binding : ISO:MGI
  • chloride ion binding : ISO:MGI
  • cysteine-type endopeptidase activity : IBA:GO_Central
  • cysteine-type peptidase activity : ISO:MGI
  • identical protein binding : ISO:MGI
  • peptidase activator activity involved in apoptotic process : IGI:MGI
  • phosphatase binding : ISO:MGI
  • protein self-association : ISO:MGI
  • serine-type endopeptidase activity : IMP:UniProtKB
GO - Biological process
  • aging : IEA:Ensembl
  • positive regulation of apoptotic signaling pathway : IGI:MGI
  • positive regulation of proteolysis involved in cellular protein catabolic process : ISO:MGI
  • proteolysis : IMP:UniProtKB
  • proteolysis involved in cellular protein catabolic process : IBA:GO_Central
  • response to organic substance : ISO:MGI
  • T cell mediated cytotoxicity : IGI:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.