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P78330

Phosphoserine phosphatase (P78330)

Uniprot ID P78330
Protein Name Phosphoserine phosphatase
Gene Name PSPH
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.719
Function Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates. .
GO - Molecular function
  • calcium ion binding : IDA:UniProtKB
  • magnesium ion binding : IDA:UniProtKB
  • phosphoserine phosphatase activity : IDA:UniProtKB
  • protein homodimerization activity : IPI:UniProtKB
GO - Biological process
  • L-serine biosynthetic process : TAS:Reactome
  • L-serine metabolic process : IDA:UniProtKB
  • response to mechanical stimulus : IEA:Ensembl
  • response to nutrient levels : IEA:Ensembl
  • response to testosterone : IEA:Ensembl
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.