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P62634

Cellular nucleic acid-binding protein (P62634)

Uniprot ID P62634
Protein Name Cellular nucleic acid-binding protein
Gene Name Cnbp
Species Rattus norvegicus (Rat)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function Single-stranded DNA-binding protein, with specificity to the sterol regulatory element (SRE). Involved in sterol-mediated repression.
GO - Molecular function
  • DNA-binding transcription repressor activity, RNA polymerase II-specific : ISO:RGD
  • mRNA binding : IBA:GO_Central
  • RNA polymerase II regulatory region sequence-specific DNA binding : ISO:RGD
  • single-stranded DNA binding : IDA:RGD
  • single-stranded RNA binding : IDA:RGD
  • translation regulator activity : IBA:GO_Central
  • zinc ion binding : IEA:InterPro
GO - Biological process
  • negative regulation of transcription by RNA polymerase II : ISO:RGD
  • positive regulation of cell population proliferation : ISS:UniProtKB
  • positive regulation of cytoplasmic translation : IBA:GO_Central
  • positive regulation of transcription by RNA polymerase II : ISS:UniProtKB
  • positive regulation of transcription, DNA-templated : ISS:UniProtKB
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.