| Signal peptide(a) |
Y |
Secretome P(b) |
0.937 |
| Function |
TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth. |
| GO - Molecular function |
- amyloid-beta binding : IDA:UniProtKB
- cytokine activity : TAS:UniProtKB
- growth factor activity : IEA:UniProtKB-KW
- protein heterodimerization activity : TAS:UniProtKB
- protein homodimerization activity : IDA:UniProtKB
- signaling receptor binding : IMP:UniProtKB
- transforming growth factor beta receptor binding : IDA:UniProtKB
- type II transforming growth factor beta receptor binding : IDA:BHF-UCL
- type III transforming growth factor beta receptor binding : IMP:AgBase
|
| GO - Biological process |
- activation of protein kinase activity : IDA:BHF-UCL
- angiogenesis : TAS:UniProtKB
- ascending aorta morphogenesis : ISS:BHF-UCL
- atrial septum morphogenesis : ISS:BHF-UCL
- atrial septum primum morphogenesis : ISS:BHF-UCL
- atrioventricular valve morphogenesis : ISS:BHF-UCL
- BMP signaling pathway : IBA:GO_Central
- cardiac epithelial to mesenchymal transition : IDA:BHF-UCL
- cardiac muscle cell proliferation : IDA:UniProtKB
- cardiac right ventricle morphogenesis : ISS:BHF-UCL
- cardioblast differentiation : IDA:UniProtKB
- cell cycle arrest : IDA:BHF-UCL
- cell death : IDA:UniProtKB
- cell development : IBA:GO_Central
- cell migration : IDA:BHF-UCL
- cell morphogenesis : IDA:UniProtKB
- cell proliferation : TAS:ProtInc
- cell-cell junction organization : IDA:BHF-UCL
- cell-cell signaling : TAS:ProtInc
- collagen fibril organization : IDA:BHF-UCL
- cranial skeletal system development : ISS:BHF-UCL
- dopamine biosynthetic process : ISS:UniProtKB
- embryo development ending in birth or egg hatching : TAS:UniProtKB
- embryonic digestive tract development : IEP:DFLAT
- embryonic limb morphogenesis : ISS:BHF-UCL
- endocardial cushion fusion : ISS:BHF-UCL
- endocardial cushion morphogenesis : ISS:BHF-UCL
- epithelial to mesenchymal transition : IDA:BHF-UCL
- extrinsic apoptotic signaling pathway : IDA:BHF-UCL
- eye development : IDA:UniProtKB
- generation of neurons : TAS:UniProtKB
- glial cell migration : IDA:BHF-UCL
- hair follicle development : IDA:UniProtKB
- hair follicle morphogenesis : ISS:UniProtKB
- heart development : IDA:UniProtKB
- heart morphogenesis : IDA:BHF-UCL
- heart valve morphogenesis : ISS:BHF-UCL
- hemopoiesis : ISS:UniProtKB
- inner ear development : ISS:BHF-UCL
- kidney development : ISS:BHF-UCL
- male gonad development : ISS:BHF-UCL
- membranous septum morphogenesis : ISS:BHF-UCL
- negative regulation of alkaline phosphatase activity : IDA:BHF-UCL
- negative regulation of angiogenesis : IDA:BHF-UCL
- negative regulation of cell growth : IDA:BHF-UCL
- negative regulation of cell proliferation : IDA:UniProtKB
- negative regulation of epithelial cell proliferation : IDA:BHF-UCL
- negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation : ISS:BHF-UCL
- negative regulation of gene expression : IDA:BHF-UCL
- negative regulation of immune response : TAS:UniProtKB
- negative regulation of macrophage cytokine production : IDA:DFLAT
- negative regulation of Ras protein signal transduction : ISS:BHF-UCL
- neural retina development : ISS:BHF-UCL
- neural tube closure : ISS:BHF-UCL
- neuron development : ISS:UniProtKB
- neutrophil chemotaxis : ISS:UniProtKB
- odontogenesis : NAS:BHF-UCL
- outflow tract septum morphogenesis : ISS:BHF-UCL
- pathway-restricted SMAD protein phosphorylation : IDA:BHF-UCL
- pharyngeal arch artery morphogenesis : ISS:BHF-UCL
- platelet degranulation : TAS:Reactome
- positive regulation of cardioblast differentiation : IDA:UniProtKB
- positive regulation of cell adhesion mediated by integrin : IDA:BHF-UCL
- positive regulation of cell cycle : ISS:UniProtKB
- positive regulation of cell division : IEA:UniProtKB-KW
- positive regulation of cell growth : IDA:UniProtKB
- positive regulation of cell proliferation : IDA:UniProtKB
- positive regulation of epithelial cell migration : IDA:BHF-UCL
- positive regulation of epithelial to mesenchymal transition : IDA:BHF-UCL
- positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation : ISS:BHF-UCL
- positive regulation of heart contraction : IDA:UniProtKB
- positive regulation of immune response : ISS:UniProtKB
- positive regulation of integrin biosynthetic process : IDA:BHF-UCL
- positive regulation of neuron apoptotic process : IDA:UniProtKB
- positive regulation of Notch signaling pathway : IDA:BHF-UCL
- positive regulation of ossification : IEP:BHF-UCL
- positive regulation of pathway-restricted SMAD protein phosphorylation : IBA:GO_Central
- positive regulation of phosphatidylinositol 3-kinase signaling : IDA:BHF-UCL
- positive regulation of pri-miRNA transcription by RNA polymerase II : IDA:BHF-UCL
- positive regulation of protein secretion : IDA:BHF-UCL
- positive regulation of stress-activated MAPK cascade : IDA:BHF-UCL
- positive regulation of timing of catagen : IDA:UniProtKB
- protein phosphorylation : IDA:BHF-UCL
- pulmonary valve morphogenesis : ISS:BHF-UCL
- regulation of apoptotic process involved in outflow tract morphogenesis : ISS:BHF-UCL
- regulation of timing of catagen : IDA:UniProtKB
- regulation of transforming growth factor beta2 production : IMP:BHF-UCL
- response to drug : IDA:UniProtKB
- response to hypoxia : IMP:BHF-UCL
- response to progesterone : IDA:BHF-UCL
- response to wounding : IEP:BHF-UCL
- salivary gland morphogenesis : IEP:BHF-UCL
- secondary palate development : ISS:BHF-UCL
- skeletal system development : ISS:BHF-UCL
- SMAD protein signal transduction : IDA:BHF-UCL
- somatic stem cell division : ISS:UniProtKB
- substantia propria of cornea development : ISS:BHF-UCL
- transforming growth factor beta receptor signaling pathway : IDA:BHF-UCL
- uterine wall breakdown : TAS:BHF-UCL
- uterus development : ISS:BHF-UCL
- ventricular septum morphogenesis : ISS:BHF-UCL
- ventricular trabecula myocardium morphogenesis : ISS:BHF-UCL
- wound healing : ISS:UniProtKB
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