Claudin-12 (P56749)

Uniprot ID	P56749
Protein Name	Claudin-12
Gene Name	CLDN12
Species	Homo sapiens (Human)

Signal peptide^(a)	N	Secretome P^(b)	0.084
Function	Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. .
GO - Molecular function	identical protein binding : ISS:UniProtKB
GO - Biological process	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules : ISS:UniProtKB

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^{(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.}
^{(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.}