| Signal peptide(a) |
N |
Secretome P(b) |
0.517 |
| Function |
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth. . |
| GO - Molecular function |
- adiponectin binding : ISS:BHF-UCL
- cadherin binding : IDA:BHF-UCL
- calcium ion binding : IBA:GO_Central
- cytoskeletal protein binding : IBA:GO_Central
- lipoprotein particle binding : IDA:UniProtKB
- low-density lipoprotein particle binding : IDA:BHF-UCL
- protein homodimerization activity : IEA:InterPro
|
| GO - Biological process |
- adherens junction organization : IBA:GO_Central
- calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules : IDA:BHF-UCL
- cell morphogenesis : IBA:GO_Central
- cell-cell adhesion : IBA:GO_Central
- cell-cell adhesion mediated by cadherin : IBA:GO_Central
- cell-cell junction assembly : IBA:GO_Central
- endothelial cell migration : IDA:BHF-UCL
- homophilic cell adhesion via plasma membrane adhesion molecules : IDA:BHF-UCL
- keratinocyte proliferation : IDA:BHF-UCL
- lamellipodium assembly : IDA:BHF-UCL
- localization within membrane : IMP:BHF-UCL
- low-density lipoprotein particle mediated signaling : IDA:BHF-UCL
- mitotic cell cycle : IEA:Ensembl
- multicellular organism development : IBA:GO_Central
- negative regulation of cell adhesion : IDA:BHF-UCL
- negative regulation of cell population proliferation : IDA:BHF-UCL
- positive regulation of calcium-mediated signaling : IDA:BHF-UCL
- positive regulation of cell migration : IDA:BHF-UCL
- positive regulation of cell-matrix adhesion : IMP:BHF-UCL
- positive regulation of endothelial cell proliferation : IMP:BHF-UCL
- positive regulation of positive chemotaxis : IDA:BHF-UCL
- positive regulation of smooth muscle cell proliferation : IMP:BHF-UCL
- positive regulation of transcription by RNA polymerase II : IMP:BHF-UCL
- Rac protein signal transduction : IMP:BHF-UCL
- regulation of endocytosis : IMP:BHF-UCL
- regulation of epidermal growth factor receptor signaling pathway : IMP:BHF-UCL
- Rho protein signal transduction : IMP:BHF-UCL
- sprouting angiogenesis : IDA:BHF-UCL
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