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P55286

Cadherin-8 (P55286)

Uniprot ID P55286
Protein Name Cadherin-8
Gene Name CDH8
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.244
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
GO - Molecular function
  • calcium ion binding : IEA:InterPro
  • identical protein binding : IEA:Ensembl
GO - Biological process
  • adherens junction organization : TAS:Reactome
  • cell adhesion : TAS:ProtInc
  • homophilic cell adhesion via plasma membrane adhesion molecules : IEA:InterPro
  • response to cold : IEA:Ensembl
  • synaptic transmission, glutamatergic : IEA:Ensembl
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.