Cadherin-6 (P55285)

Uniprot ID P55285
Protein Name Cadherin-6
Gene Name CDH6
Species Homo sapiens (Human)
Signal peptide(a) Y Secretome P(b) 0.117
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
GO - Molecular function
  • calcium ion binding : IEA:InterPro
GO - Biological process
  • adherens junction organization : TAS:Reactome
  • cell adhesion : TAS:ProtInc
  • homophilic cell adhesion via plasma membrane adhesion molecules : IEA:InterPro
  • Notch signaling pathway : IEA:Ensembl
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.