Cadherin-6 (P55280)

Uniprot ID P55280
Protein Name Cadherin-6
Gene Name Cdh6
Species Rattus norvegicus (Rat)
Signal peptide(a) Y Secretome P(b)
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
GO - Molecular function
  • cadherin binding : IBA:GO_Central
  • calcium ion binding : IBA:GO_Central
  • cytoskeletal protein binding : IBA:GO_Central
GO - Biological process
  • adherens junction organization : IBA:GO_Central
  • calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules : IBA:GO_Central
  • cell morphogenesis : IBA:GO_Central
  • cell-cell adhesion : IBA:GO_Central
  • cell-cell adhesion mediated by cadherin : IBA:GO_Central
  • cell-cell junction assembly : IBA:GO_Central
  • female gonad development : IEP:RGD
  • homophilic cell adhesion via plasma membrane adhesion molecules : IBA:GO_Central
  • multicellular organism development : IBA:GO_Central
  • Notch signaling pathway : ISO:RGD
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.