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P55260

Annexin A4 (P55260)

Uniprot ID P55260
Protein Name Annexin A4
Gene Name Anxa4
Species Rattus norvegicus (Rat)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. .
GO - Molecular function
  • calcium ion binding : ISO:RGD
  • calcium-dependent phospholipid binding : ISO:RGD
  • calcium-dependent protein binding : ISO:RGD
  • chondroitin sulfate binding : IBA:GO_Central
  • heparin binding : IBA:GO_Central
  • identical protein binding : ISO:RGD
  • NF-kappaB binding : ISO:RGD
GO - Biological process
  • epithelial cell differentiation : ISO:RGD
  • exocytosis : NAS:RGD
  • negative regulation of interleukin-8 secretion : ISO:RGD
  • negative regulation of NF-kappaB transcription factor activity : ISO:RGD
  • Notch signaling pathway : ISO:RGD
  • regulation of transcription by RNA polymerase II : ISO:RGD
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.