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P55067

Neurocan core protein (P55067)

Uniprot ID P55067
Protein Name Neurocan core protein
Gene Name Ncan
Species Rattus norvegicus (Rat)
Basic Information Experiments (2) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b)
Function May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan; binds to hyaluronic acid.
GO - Molecular function
  • calcium ion binding : IEA:InterPro
  • carbohydrate binding : IEA:UniProtKB-KW
  • hyaluronic acid binding : IEA:UniProtKB-KW
GO - Biological process
  • cell adhesion : IEA:UniProtKB-KW
  • central nervous system development : IBA:GO_Central
  • regulation of synapse structural plasticity : ISO:RGD
  • skeletal system development : IBA:GO_Central
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.