Elastin (P54320)

Uniprot ID P54320
Protein Name Elastin
Gene Name Eln
Species Mus musculus (Mouse)
Signal peptide(a) Y Secretome P(b) 0.171
Function Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle. .
GO - Molecular function
  • extracellular matrix binding : IDA:MGI
  • extracellular matrix structural constituent : IEA:InterPro
GO - Biological process
  • extracellular matrix organization : IDA:MGI
  • regulation of actin filament polymerization : IMP:MGI
  • skeletal muscle tissue development : IMP:MGI
  • stress fiber assembly : IMP:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.