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P53657

Pyruvate kinase PKLR (P53657)

Uniprot ID P53657
Protein Name Pyruvate kinase PKLR
Gene Name Pklr
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.0
Function Plays a key role in glycolysis. .
GO - Molecular function
  • ATP binding : IEA:UniProtKB-KW
  • kinase activity : IEA:UniProtKB-KW
  • magnesium ion binding : IEA:InterPro
  • potassium ion binding : IEA:InterPro
  • pyruvate kinase activity : IDA:MGI
GO - Biological process
  • ATP biosynthetic process : ISO:MGI
  • carbohydrate metabolic process : ISO:MGI
  • cellular response to insulin stimulus : ISO:MGI
  • endocrine pancreas development : TAS:Reactome
  • glycolytic process : ISO:MGI
  • pyruvate biosynthetic process : ISO:MGI
  • response to ATP : ISO:MGI
  • response to cAMP : ISO:MGI
  • response to heat : ISO:MGI
  • response to lithium ion : ISO:MGI
  • response to other organism : IMP:MGI
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.