| Signal peptide(a) |
N |
Secretome P(b) |
0.28 |
| Function |
Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. |
| GO - Molecular function |
- chemoattractant activity : IDA:UniProtKB
- growth factor activity : IBA:GO_Central
- heparin binding : IEA:UniProtKB-KW
- identical protein binding : IEA:Ensembl
- vascular endothelial growth factor receptor 1 binding : IPI:UniProtKB
- vascular endothelial growth factor receptor binding : IBA:GO_Central
|
| GO - Biological process |
- angiogenesis : IBA:GO_Central
- cardiac muscle contraction : IEA:Ensembl
- coronary vasculature development : IEA:Ensembl
- induction of positive chemotaxis : IDA:UniProtKB
- negative regulation of apoptotic process : IDA:UniProtKB
- negative regulation of gene expression : IDA:UniProtKB
- negative regulation of neuron apoptotic process : IDA:UniProtKB
- platelet degranulation : TAS:Reactome
- positive regulation of angiogenesis : IBA:GO_Central
- positive regulation of cell division : IEA:UniProtKB-KW
- positive regulation of endothelial cell proliferation : IDA:UniProtKB
- positive regulation of ERK1 and ERK2 cascade : IDA:UniProtKB
- positive regulation of mast cell chemotaxis : IDA:UniProtKB
- positive regulation of peptidyl-tyrosine phosphorylation : IDA:UniProtKB
- positive regulation of protein kinase B signaling : IDA:UniProtKB
- positive regulation of protein phosphorylation : IBA:GO_Central
- positive regulation of vascular endothelial growth factor receptor signaling pathway : IDA:UniProtKB
- positive regulation of vascular wound healing : IDA:UniProtKB
- protein O-linked glycosylation : IEA:Ensembl
- response to drug : IEA:Ensembl
- response to hypoxia : IBA:GO_Central
- sprouting angiogenesis : IBA:GO_Central
- vascular endothelial growth factor receptor signaling pathway : IBA:GO_Central
- vascular endothelial growth factor signaling pathway : IBA:GO_Central
|