Thrombospondin-3 (P49746)

Uniprot ID	P49746
Protein Name	Thrombospondin-3
Gene Name	THBS3
Species	Homo sapiens (Human)

Signal peptide^(a)	N	Secretome P^(b)	0.565
Function	Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen.
GO - Molecular function	calcium ion binding : NAS:UniProtKB heparin binding : IDA:MGI
GO - Biological process	bone trabecula formation : IEA:Ensembl cell-matrix adhesion : NAS:UniProtKB growth plate cartilage development : IEA:Ensembl ossification involved in bone maturation : IEA:Ensembl

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^{(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.}
^{(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.}