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P48377

MHC class II regulatory factor RFX1 (P48377)

Uniprot ID P48377
Protein Name MHC class II regulatory factor RFX1
Gene Name Rfx1
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (1) Interactions
Signal peptide(a) N Secretome P(b) 0.492
Function Regulatory factor essential for MHC class II genes expression. Binds to the X boxes of MHC class II genes (By similarity). .
GO - Molecular function
  • DNA binding : IDA:MGI
  • DNA binding transcription factor activity : IBA:GO_Central
  • RNA polymerase II proximal promoter sequence-specific DNA binding : IBA:GO_Central
GO - Biological process
  • immune response : IBA:GO_Central
  • regulation of transcription by RNA polymerase II : IBA:GO_Central
  • transcription, DNA-templated : IEA:UniProtKB-KW
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.