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P48163

NADP-dependent malic enzyme (P48163)

Uniprot ID P48163
Protein Name NADP-dependent malic enzyme
Gene Name ME1
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.541
Function
GO - Molecular function
  • ADP binding : TAS:UniProtKB
  • electron transfer activity : TAS:UniProtKB
  • malate dehydrogenase (decarboxylating) (NAD+) activity : IEA:InterPro
  • malate dehydrogenase (decarboxylating) (NADP+) activity : IDA:UniProtKB
  • malic enzyme activity : IDA:UniProtKB
  • manganese ion binding : IDA:UniProtKB
  • NAD binding : TAS:UniProtKB
  • NADP binding : TAS:UniProtKB
  • oxaloacetate decarboxylase activity : IEA:UniProtKB-EC
GO - Biological process
  • carbohydrate metabolic process : NAS:ProtInc
  • malate metabolic process : IDA:UniProtKB
  • NADP biosynthetic process : TAS:UniProtKB
  • protein tetramerization : IEA:Ensembl
  • pyruvate metabolic process : IBA:GO_Central
  • regulation of lipid metabolic process : TAS:Reactome
  • regulation of NADP metabolic process : IMP:CACAO
  • response to carbohydrate : TAS:UniProtKB
  • response to hormone : ISS:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.