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P46926

Glucosamine-6-phosphate isomerase 1 (P46926)

Uniprot ID P46926
Protein Name Glucosamine-6-phosphate isomerase 1
Gene Name GNPDA1
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b) 0.479
Function Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity). .
GO - Molecular function
  • glucosamine-6-phosphate deaminase activity : IMP:UniProtKB
  • identical protein binding : IBA:GO_Central
GO - Biological process
  • carbohydrate metabolic process : IEA:UniProtKB-KW
  • generation of precursor metabolites and energy : IMP:UniProtKB
  • glucosamine catabolic process : IMP:UniProtKB
  • N-acetylglucosamine catabolic process : IBA:GO_Central
  • N-acetylneuraminate catabolic process : IBA:GO_Central
  • single fertilization : TAS:ProtInc
  • UDP-N-acetylglucosamine biosynthetic process : IBA:GO_Central
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.