Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (P45700)

Uniprot ID	P45700
Protein Name	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA
Gene Name	Man1a1
Species	Mus musculus (Mouse)

Signal peptide^(a)	N	Secretome P^(b)	0.501
Function	Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
GO - Molecular function	calcium ion binding : IEA:InterPro mannosyl-oligosaccharide 1,2-alpha-mannosidase activity : IBA:GO_Central
GO - Biological process	N-glycan processing : IBA:GO_Central protein glycosylation : IEA:UniProtKB-UniPathway

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^{(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.}
^{(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.}