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P42830

C-X-C motif chemokine 5 (P42830)

Uniprot ID P42830
Protein Name C-X-C motif chemokine 5
Gene Name CXCL5
Species Homo sapiens (Human)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.815
Function Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. .
GO - Molecular function
  • chemokine activity : IBA:GO_Central
  • identical protein binding : IDA:UniProtKB
GO - Biological process
  • antimicrobial humoral immune response mediated by antimicrobial peptide : IBA:GO_Central
  • cell-cell signaling : TAS:ProtInc
  • cellular response to lipopolysaccharide : IBA:GO_Central
  • chemokine-mediated signaling pathway : IBA:GO_Central
  • chemotaxis : TAS:ProtInc
  • G protein-coupled receptor signaling pathway : TAS:Reactome
  • immune response : IBA:GO_Central
  • inflammatory response : IBA:GO_Central
  • leukocyte chemotaxis : IBA:GO_Central
  • neutrophil chemotaxis : IBA:GO_Central
  • positive regulation of cell population proliferation : TAS:ProtInc
  • signal transduction : TAS:ProtInc
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.