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P41562

Isocitrate dehydrogenase [NADP] cytoplasmic (P41562)

Uniprot ID P41562
Protein Name Isocitrate dehydrogenase [NADP] cytoplasmic
Gene Name Idh1
Species Rattus norvegicus (Rat)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) N Secretome P(b)
Function
GO - Molecular function
  • identical protein binding : ISO:RGD
  • isocitrate dehydrogenase (NADP+) activity : IDA:RGD
  • isocitrate dehydrogenase activity : ISO:RGD
  • magnesium ion binding : ISS:UniProtKB
  • NAD binding : IEA:InterPro
  • NADP binding : IDA:RGD
  • protein homodimerization activity : ISO:RGD
GO - Biological process
  • 2-oxoglutarate metabolic process : ISS:UniProtKB
  • female gonad development : IEP:RGD
  • glutathione metabolic process : ISO:RGD
  • glyoxylate cycle : IEA:UniProtKB-KW
  • isocitrate metabolic process : IDA:RGD
  • NADP metabolic process : IBA:GO_Central
  • regulation of phospholipid biosynthetic process : ISO:RGD
  • regulation of phospholipid catabolic process : ISO:RGD
  • response to organic cyclic compound : IDA:RGD
  • response to oxidative stress : ISO:RGD
  • response to steroid hormone : IDA:RGD
  • tricarboxylic acid cycle : IEA:UniProtKB-KW
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.