Home Proteins Experiments Diseases Interactions Tutorial
Home
/
Proteins
/
P35456

Urokinase plasminogen activator surface receptor (P35456)

Uniprot ID P35456
Protein Name Urokinase plasminogen activator surface receptor
Gene Name Plaur
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (0) Interactions
Signal peptide(a) Y Secretome P(b) 0.448
Function Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA.
GO - Molecular function
  • enzyme binding : ISO:MGI
  • protein domain specific binding : ISO:MGI
  • signaling receptor binding : ISO:MGI
  • urokinase plasminogen activator receptor activity : ISO:MGI
GO - Biological process
  • epithelial cell differentiation involved in prostate gland development : ISO:MGI
  • mesenchymal cell differentiation : ISO:MGI
  • negative regulation of apoptotic process : ISO:MGI
  • negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway : ISO:MGI
  • negative regulation of intrinsic apoptotic signaling pathway : ISO:MGI
  • positive regulation of DNA binding : ISO:MGI
  • positive regulation of epidermal growth factor receptor signaling pathway : ISO:MGI
  • positive regulation of gene expression : ISO:MGI
  • positive regulation of protein phosphorylation : ISO:MGI
  • positive regulation of release of cytochrome c from mitochondria : ISO:MGI
  • urokinase plasminogen activator signaling pathway : IBA:GO_Central
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.