| Signal peptide(a) |
Y |
Secretome P(b) |
0.362 |
| Function |
May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3 (By similarity). . |
| GO - Molecular function |
- calcium ion binding : ISO:MGI
- collagen binding : ISO:MGI
- core promoter binding : ISO:MGI
- metalloendopeptidase activity : ISO:MGI
- sequence-specific DNA binding : ISO:MGI
- serine-type endopeptidase activity : TAS:Reactome
- zinc ion binding : ISO:MGI
|
| GO - Biological process |
- cellular response to virus : IMP:CAFA
- negative regulation of transcription by RNA polymerase II : IMP:CAFA
- negative regulation of type I interferon-mediated signaling pathway : IMP:CAFA
- positive regulation of epithelial cell proliferation involved in wound healing : ISO:MGI
- positive regulation of gene expression : IMP:CAFA
- positive regulation of interferon-alpha secretion : IMP:CAFA
- positive regulation of transcription by RNA polymerase II : ISO:MGI
- positive regulation of type I interferon-mediated signaling pathway : IMP:CAFA
- protein import into nucleus : IMP:CAFA
- proteolysis : ISO:MGI
- regulation of defense response to virus by host : IMP:CAFA
- regulation of trophoblast cell migration : ISO:MGI
- wound healing, spreading of epidermal cells : ISO:MGI
|