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P34902

Cytokine receptor common subunit gamma (P34902)

Uniprot ID P34902
Protein Name Cytokine receptor common subunit gamma
Gene Name Il2rg
Species Mus musculus (Mouse)
Basic Information Experiments (1) Disease (1) Interactions
Signal peptide(a) Y Secretome P(b) 0.175
Function Common subunit for the receptors for a variety of interleukins.
GO - Molecular function
  • cytokine receptor activity : IEA:InterPro
  • interleukin-2 binding : IPI:MGI
GO - Biological process
  • positive regulation of B cell differentiation : IMP:MGI
  • positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation : IMP:MGI
  • positive regulation of gene expression : IMP:MGI
  • positive regulation of lymphocyte differentiation : IMP:MGI
  • positive regulation of T cell differentiation in thymus : IMP:MGI
  • regulation of gene expression : IMP:MGI
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(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.