Uniprot ID | P32507 | ||
Protein Name | Nectin-2 | ||
Gene Name | Nectin2 | ||
Species | Mus musculus (Mouse) |
Signal peptide(a) | Y | Secretome P(b) | 0.14 |
Function | Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein. . | ||
GO - Molecular function |
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GO - Biological process |
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