| Signal peptide(a) |
N |
Secretome P(b) |
0.305 |
| Function |
Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes. . |
| GO - Molecular function |
- actin binding : IDA:UniProtKB
- cytokine binding : IPI:UniProtKB
- enzyme binding : IPI:UniProtKB
- GDP binding : IDA:CAFA
- GTP binding : IDA:CAFA
- GTPase activity : IDA:CAFA
- Hsp90 protein binding : IPI:UniProtKB
- identical protein binding : IPI:IntAct
- protein homodimerization activity : IDA:UniProtKB
- spectrin binding : IPI:UniProtKB
|
| GO - Biological process |
- cellular response to interferon-gamma : IDA:UniProtKB
- cellular response to interleukin-1 : IEP:UniProtKB
- cellular response to tumor necrosis factor : IEP:UniProtKB
- defense response to virus : IEA:UniProtKB-KW
- interferon-gamma-mediated signaling pathway : TAS:Reactome
- negative regulation of ERK1 and ERK2 cascade : IMP:UniProtKB
- negative regulation of interleukin-2 secretion : IMP:UniProtKB
- negative regulation of protein localization to plasma membrane : IMP:UniProtKB
- negative regulation of substrate adhesion-dependent cell spreading : IMP:UniProtKB
- negative regulation of T cell receptor signaling pathway : IMP:UniProtKB
- protein homooligomerization : IDA:CAFA
- protein localization to vacuole : IDA:UniProtKB
- regulation of calcium-mediated signaling : IMP:UniProtKB
- regulation of protein localization to plasma membrane : IGI:UniProtKB
|