Cytidine deaminase (P32320)

Uniprot ID P32320
Protein Name Cytidine deaminase
Gene Name CDA
Species Homo sapiens (Human)
Signal peptide(a) N Secretome P(b) 0.889
Function This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
GO - Molecular function
  • cytidine deaminase activity : IDA:UniProtKB
  • identical protein binding : IPI:UniProtKB
  • nucleoside binding : IDA:UniProtKB
  • protein homodimerization activity : IDA:UniProtKB
  • zinc ion binding : IDA:UniProtKB
GO - Biological process
  • cell surface receptor signaling pathway : NAS:UniProtKB
  • cytidine deamination : IDA:UniProtKB
  • cytosine metabolic process : TAS:UniProtKB
  • negative regulation of cell growth : IDA:UniProtKB
  • negative regulation of nucleotide metabolic process : IDA:UniProtKB
  • neutrophil degranulation : TAS:Reactome
  • pyrimidine nucleoside salvage : TAS:Reactome
  • pyrimidine-containing compound salvage : NAS:UniProtKB
Back
(a) The Signal peptide D-score cutoff for "YES"(having signal peptide) is 0.45.
(b) Non-classically secreted proteins should obtain an NN-score(Neural Networks score) exceeding the normal threshold of 0.5, but not at the same time be predicted to contain a signal peptide.